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Chemical & Physical Properties of Select Polymers

 

Chemical Properties

 

Polymer Inherent Viscosity
(dL/g)
Crystalline Melt Transition
(°C)
Glass Transition Temp
(°C)
Solubility
(at 5% w/w)
Approx. Resorption
(months)
Solvents (partial listing only)
1 = dichloromethane 2 = tetrahydrofuran 3 = ethyl acetate 4 = chloroform 5 = hexafluoroisopropanol 6 = acetone
50:50 DL-PLG 0.55 - 0.75 Amorphous 45 - 50 1 2 3 4 5 6 1 - 2
65:35 DL-PLG 0.55 - 0.75 Amorphous 45 - 50 1 2 3 4 5 6 3 - 4
75:25 DL-PLG 0.55 - 0.75 Amorphous 50 - 55 1 2 3 4 5 6 4 - 5
85:15 DL-PLG 0.55 - 0.75 Amorphous 50 - 55 1 2 3 4 5 6 5 - 6
DL-PLA 0.55 - 0.75 Amorphous 50 - 60 1 2 3 4 5 6 12 - 16
L-PLA 0.90 - 1.20 173 - 178 60 - 65 1 4 5 >24
PGA 1.40 - 1.80 225 - 230 35 - 40 5 6 - 12
PCL 1.00 - 1.30 58-63 (-65) - (-60) 1 4 5 >24
25:75 DL-PLCL 0.70 - 0.90 Amorphous (-50) - (-40) 1 4 5  
80:20 DL-PLCL 0.70 - 0.90 Amorphous 17 - 23 1 4 5  

 

Physical Properties

 

Polymer Density
(g/mL)
Tensile Strength
(psi)
Elongation
(%)
Modulus
(psi)
DL-PLG = poly(DL-lactide-co-glycolide) DL-PLA = poly(DL-lactide) L-PLA = poly(L-lactide)
PGA = poly(glycolide) PCL= poly(ε-caprolactone)
50:50 DL-PLG 1.34 6000 - 8000 3 - 10 2 - 4x105
65:35 DL-PLG 1.30 6000 - 8000 3 - 10 2 - 4x105
75:25 DL-PLG 1.30 6000 - 8000 3 - 10 2 - 4x105
85:15 DL-PLG 1.27 6000 - 8000 3 - 10 2 - 4x105
DL-PLA 1.25 4000 - 6000 3 - 10 2 - 4x105
L-PLA 1.24 8000 - 12000 5 -10 4 - 6x105
PGA 1.53 10000+ 15 - 20 1x106+
PCL 1.11 3000 - 5000 300 - 500 3 - 5x104
25:75 DL-PLCL 1.15 ~1100 ~600 5x104 - 2x105
80:20 DL-PLCL 1.22 ~750 ~150 6x104 - 2x105

Order Polymers

We offer a variety of polymers and sample kits in stock for prompt delivery.

Standard Products

A complete list of Standard Product pharmaceutical grade polymers available from LACTEL.

Custom Polymers

If additional product optimization is required, we can provide developmental input and custom synthesis. A large percentage of our polymer business at DURECT is devoted to the development of polymers with customized characteristics.

Safety Data Sheets

 

The following Safety Data Sheets are saved in a format that can be viewed and printed from Acrobat Reader.
CONTACT US:

LACTEL Absorbable Polymers

2200 Riverchase Center, Suite 501
Birmingham, AL 35244 USA


Customer Service:


Phone: (877) 705-8072 Fax: (408) 865-1406

E-mail: absorbablescs@durect.com

LACTEL Technical Support:

Phone: (205) 578-5102

E-mail: absorbables@durect.com